Gip上昇抑制剤の評価又は選択方法

  • Inventors:
  • Assignees: 花王株式会社
  • Publication Date: October 30, 2013
  • Publication Number: JP-5328595-B2

Abstract

<P>PROBLEM TO BE SOLVED: To provide a method of evaluating or selecting a GIP elevation inhibitor. <P>SOLUTION: The method of evaluating or selecting a GIP elevation inhibitor includes processes of: bringing a test substance into contact with a tissue or cell originating from a mammal capable of manifesting a FAT/CD 36 gene or a FAT/CD36 protein (A); measuring the amount of manifestation of the FAT/CD36 gene or FAT/CD36 protein in a tissue or cell originating from the mammal (B); comparing the amount of manifestation measured in (B) in the above with the amount of manifestation of the FAT/CD 36 gene or FAT/CD36 protein in a comparison group for preventing a test substance from abutting on a tissue or cell originating from a mammal capable of manifesting the FAT/CD36 gene or FAT/CD36 protein (C); and evaluating or selecting the test substance for reducing the amount of manifestation of the FAT/CD36 gene or FAT/CD36 protein as a GIP elevation inhibitor, based on the result of (C) in the above (D). <P>COPYRIGHT: (C)2011,JPO&amp;INPIT

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